Why it matters

Why does retinal imaging equipment need tighter standardisation than most other trial imaging?
Ophthalmology endpoints, such as changes measured by optical coherence tomography or fundus photography, depend on subtle, small-scale differences that can be affected by even minor variation in imaging equipment or calibration between sites. A trial can end up comparing equipment differences rather than treatment effects if that standardisation isn't tightly controlled.

Visual acuity testing depends on the room as much as the chart
Standardised visual acuity testing needs consistent lighting and chart calibration to produce comparable results across sites, since even small variations in illumination can shift a patient's measured acuity.

Gene therapy for inherited retinal disease has brought cold chain into ophthalmology
A growing number of ophthalmology trials involve gene therapies for inherited retinal conditions, which need the same cryogenic storage and chain-of-custody discipline used in other cell and gene therapy research.


What we do

Our global distribution network puts calibrated equipment on site for ophthalmology studies anywhere in the world, whenever it's needed. Specialist ophthalmology equipment covers imaging and diagnostic devices. Cold chain and sample processing covers centrifuges, refrigerators, and freezers. Day-to-day site operations covers thermometers, temperature dataloggers, and scales. Everything is available fully calibrated and ready to use. If you require equipment supply for an ophthalmology study, get in touch.

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Our 35+ years of experience with product knowledge, sourcing quality, regulatory intelligence and logistical knowhow makes us experts in what we do.

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References

* https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-022-14491-0
** https://www.who.int/news-room/fact-sheets/detail/blindness-and-visual-impairment
*** https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920965/
**** https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(20)30488-5/fulltext